JOINT FILER INFORMATION
--------------------------



NAME: Frost Gamma Investments Trust

ADDRESS: 4400 Biscayne Blvd
Miami, FL 33137

Designated Filer: Phillip Frost, M.D.

Issuer and Ticker Symbol: Opko Health, Inc. (OPK)

Date of Event Requiring
Statement: July 20, 2007





FROST GAMMA INVESTMENTS TRUST

by: /s/ Phillip Frost, M.D., Trustee
-------------------------------------
Phillip Frost, M.D., Trustee