Published on September 5, 2007
JOINT FILER INFORMATION
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NAME: Frost Gamma Investments Trust
ADDRESS: 4400 Biscayne Blvd
Miami, FL 33137
Designated Filer: Phillip Frost, M.D.
Issuer and Ticker Symbol: Opko Health, Inc. (OPK)
Date of Event
Requiring Statement: August 31, 2007
FROST GAMMA INVESTMENTS TRUST
by: /s/ Phillip Frost MD
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Phillip Frost, M.D., Trustee