Published on March 14, 2008
JOINT FILER INFORMATION
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NAME: Frost Gamma Investments Trust
ADDRESS: 4400 Biscayne Blvd
Miami, FL 33137
Designated Filer: Phillip Frost, M.D.
Issuer and Ticker Symbol: Opko Health, Inc. (OPK)
Date of Event Requiring
Statement: March 12, 2008
FROST GAMMA INVESTMENTS TRUST
by: /s/ Phillip Frost MD, as trustee
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Phillip Frost, M.D., Trustee