Form: 4

Statement of changes in beneficial ownership of securities

April 3, 2008

Published on April 3, 2008

Exhibit 99


JOINT FILER INFORMATION




NAME: Frost Gamma Investments Trust

ADDRESS: 4400 Biscayne Blvd
Miami, FL 33137

Designated Filer: Phillip Frost, M.D.

Issuer and Ticker Symbol: Opko Health, Inc. (OPK)

Date of Event Requiring
Statement: April 1, 2008








FROST GAMMA INVESTMENTS TRUST



by: /s/ Phillip Frost M.D., as trustee
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Phillip Frost, M.D., Trustee