Board Committees

Mr. Pfenniger has served as a director of OPKO since January 2008. Mr. Pfenniger served as CEO and President for Continucare Corporation, a provider of primary care physician and practice management services, and as Chairman of the Board of Directors of Continucare Corporation until 2011. Mr. Pfenniger has also served as the CEO and Vice Chairman of Whitman Education Group, Inc.

Prior to joining Whitman, he served as the Chief Operating Officer of IVAX and as the Senior Vice President-Legal Affairs and General Counsel of IVAX. Mr. Pfenniger currently serves as a director of GP Strategies Corporation, a corporate education and training company, TransEnterix Inc., a medical device company pioneering the use of robotics, IntegraMed America, and BioCardia, Inc., a clinical-stage regenerative medicine company. He also serves as the Vice Chairman of the Board of Trustees and as a member of the Executive Committee of the Phillip and Patricia Frost Museum of Science.

Dr. Krasno was appointed to the OPKO Board in 2017. Previously, Dr. Krasno served as executive director of the William R. Kenan, Jr. Charitable Trust and as President of the four affiliated William R. Kenan, Jr. Funds.

Prior to joining the Trust, Dr. Krasno was the President of the Monterey Institute of International Studies in Monterey, California. Dr. Krasno also served as a director of the University of North Carolina Health Care System and as chairman of the board of directors until 2012. He has also served as President and Chief Executive Officer of the Institute of International Education in New York, and as Deputy Assistant Secretary of Education in Washington, D.C.

Dr. Krasno currently serves as a director of Ladenburg Thalmann and BioCardia, Inc. and previously served as a director of Castle Brands, Inc. Dr. Krasno holds a Bachelor of Science from the University of Illinois and a Ph.D. from Stanford University.

Dr. Lachman is a healthcare investment manager with more than 35 years of experience in portfolio management, biopharmaceutical investment research and healthcare investment banking. Additionally, Dr. Lachman is supported by a foundation in medicine and gastroenterology research. Dr. Lachman founded Maximus Capital, LLC in 2001 and currently serves as its general partner. Dr. Lachman previously served as the general partner of The Galleon Group from 1998 to 2001 and as Managing Director, Investment Research at Goldman Sachs & Co. from 1989 to 1998. Dr. Lachman is a Directors Council board member of the Museum of Modern Art, a patron of the Metropolitan Opera, and a board member of the Department of Surgery at Mount Sinai Medical Center in New York.

Mr. Paganelli has served as a director of OPKO since December 2003. Previously, Mr. Paganelli served as OPKO's Interim CEO and secretary, and Chairman of OPKO's Board of Directors until 2007. Mr. Paganelli also served as President and CEO of Transamerica Life Insurance Company of New York.

Since 1987, Mr. Paganelli has been a partner in RFG Associates, a financial planning organization. Mr. Paganelli is also the Managing Partner of Pharos Systems Partners, LLC, an investment company, and served as Chairman of the Board of Pharos Systems International, a software company, from 2001 until March 2021. He was Vice President and Executive Vice President of PEG Capital Management, an investment advisory organization. Mr. Paganelli was also an officer and director-stockholder of Mike Barnard Chevrolet, Inc., an automobile dealership. Mr. Paganelli also serves as a director of Western New York Energy, LLC. Mr. Paganelli previously served on the Board of Trustees of Paul Smith's College and the Board of Managers of Bridge Financial Services, LLC.

Dr. Krasno was appointed to the OPKO Board in 2017. Previously, Dr. Krasno served as executive director of the William R. Kenan, Jr. Charitable Trust and as President of the four affiliated William R. Kenan, Jr. Funds.

Prior to joining the Trust, Dr. Krasno was the President of the Monterey Institute of International Studies in Monterey, California. Dr. Krasno also served as a director of the University of North Carolina Health Care System and as chairman of the board of directors until 2012. He has also served as President and Chief Executive Officer of the Institute of International Education in New York, and as Deputy Assistant Secretary of Education in Washington, D.C.

Dr. Krasno currently serves as a director of Ladenburg Thalmann and BioCardia, Inc. and previously served as a director of Castle Brands, Inc. Dr. Krasno holds a Bachelor of Science from the University of Illinois and a Ph.D. from Stanford University.

Dr. Lachman is a healthcare investment manager with more than 35 years of experience in portfolio management, biopharmaceutical investment research and healthcare investment banking. Additionally, Dr. Lachman is supported by a foundation in medicine and gastroenterology research. Dr. Lachman founded Maximus Capital, LLC in 2001 and currently serves as its general partner. Dr. Lachman previously served as the general partner of The Galleon Group from 1998 to 2001 and as Managing Director, Investment Research at Goldman Sachs & Co. from 1989 to 1998. Dr. Lachman is a Directors Council board member of the Museum of Modern Art, a patron of the Metropolitan Opera, and a board member of the Department of Surgery at Mount Sinai Medical Center in New York.

Dr. Medel is the co-founder of MEDNAX, Inc., a national health solutions partner comprised of the nation’s leading providers of physician services, and has served as a director of MEDNAX since 1979. Dr. Medel served as MEDNAX’s President until May 2000 and again from March 2003 until May 2004. He served as Chief Executive Officer of MEDNAX from 1979 until December 2002, and again from March 2003 until July 2020 when he retired. Dr. Medel has served as a member of the Board of Trustees of the Dana Farber Cancer Institute, Inc. since January 2016. He was a member of the Board of Trustees of the University of Miami from January 2004 to February 2012. Dr. Medel actively participates as a member of several medical and professional organizations and from June 2006 to April 2009, served on the Board of Directors of MBF Healthcare Acquisition Corp.

Mr. Paganelli has served as a director of OPKO since December 2003. Previously, Mr. Paganelli served as OPKO's Interim CEO and secretary, and Chairman of OPKO's Board of Directors until 2007. Mr. Paganelli also served as President and CEO of Transamerica Life Insurance Company of New York.

Since 1987, Mr. Paganelli has been a partner in RFG Associates, a financial planning organization. Mr. Paganelli is also the Managing Partner of Pharos Systems Partners, LLC, an investment company, and served as Chairman of the Board of Pharos Systems International, a software company, from 2001 until March 2021. He was Vice President and Executive Vice President of PEG Capital Management, an investment advisory organization. Mr. Paganelli was also an officer and director-stockholder of Mike Barnard Chevrolet, Inc., an automobile dealership. Mr. Paganelli also serves as a director of Western New York Energy, LLC. Mr. Paganelli previously served on the Board of Trustees of Paul Smith's College and the Board of Managers of Bridge Financial Services, LLC.

Dr. Lachman is a healthcare investment manager with more than 35 years of experience in portfolio management, biopharmaceutical investment research and healthcare investment banking. Additionally, Dr. Lachman is supported by a foundation in medicine and gastroenterology research. Dr. Lachman founded Maximus Capital, LLC in 2001 and currently serves as its general partner. Dr. Lachman previously served as the general partner of The Galleon Group from 1998 to 2001 and as Managing Director, Investment Research at Goldman Sachs & Co. from 1989 to 1998. Dr. Lachman is a Directors Council board member of the Museum of Modern Art, a patron of the Metropolitan Opera, and a board member of the Department of Surgery at Mount Sinai Medical Center in New York.

Dr. Medel is the co-founder of MEDNAX, Inc., a national health solutions partner comprised of the nation’s leading providers of physician services, and has served as a director of MEDNAX since 1979. Dr. Medel served as MEDNAX’s President until May 2000 and again from March 2003 until May 2004. He served as Chief Executive Officer of MEDNAX from 1979 until December 2002, and again from March 2003 until July 2020 when he retired. Dr. Medel has served as a member of the Board of Trustees of the Dana Farber Cancer Institute, Inc. since January 2016. He was a member of the Board of Trustees of the University of Miami from January 2004 to February 2012. Dr. Medel actively participates as a member of several medical and professional organizations and from June 2006 to April 2009, served on the Board of Directors of MBF Healthcare Acquisition Corp.

Dr. Krasno was appointed to the OPKO Board in 2017. Previously, Dr. Krasno served as executive director of the William R. Kenan, Jr. Charitable Trust and as President of the four affiliated William R. Kenan, Jr. Funds.

Prior to joining the Trust, Dr. Krasno was the President of the Monterey Institute of International Studies in Monterey, California. Dr. Krasno also served as a director of the University of North Carolina Health Care System and as chairman of the board of directors until 2012. He has also served as President and Chief Executive Officer of the Institute of International Education in New York, and as Deputy Assistant Secretary of Education in Washington, D.C.

Dr. Krasno currently serves as a director of Ladenburg Thalmann and BioCardia, Inc. and previously served as a director of Castle Brands, Inc. Dr. Krasno holds a Bachelor of Science from the University of Illinois and a Ph.D. from Stanford University.

Dr. Lachman is a healthcare investment manager with more than 35 years of experience in portfolio management, biopharmaceutical investment research and healthcare investment banking. Additionally, Dr. Lachman is supported by a foundation in medicine and gastroenterology research. Dr. Lachman founded Maximus Capital, LLC in 2001 and currently serves as its general partner. Dr. Lachman previously served as the general partner of The Galleon Group from 1998 to 2001 and as Managing Director, Investment Research at Goldman Sachs & Co. from 1989 to 1998. Dr. Lachman is a Directors Council board member of the Museum of Modern Art, a patron of the Metropolitan Opera, and a board member of the Department of Surgery at Mount Sinai Medical Center in New York.

Mr. Paganelli has served as a director of OPKO since December 2003. Previously, Mr. Paganelli served as OPKO's Interim CEO and secretary, and Chairman of OPKO's Board of Directors until 2007. Mr. Paganelli also served as President and CEO of Transamerica Life Insurance Company of New York.

Since 1987, Mr. Paganelli has been a partner in RFG Associates, a financial planning organization. Mr. Paganelli is also the Managing Partner of Pharos Systems Partners, LLC, an investment company, and served as Chairman of the Board of Pharos Systems International, a software company, from 2001 until March 2021. He was Vice President and Executive Vice President of PEG Capital Management, an investment advisory organization. Mr. Paganelli was also an officer and director-stockholder of Mike Barnard Chevrolet, Inc., an automobile dealership. Mr. Paganelli also serves as a director of Western New York Energy, LLC. Mr. Paganelli previously served on the Board of Trustees of Paul Smith's College and the Board of Managers of Bridge Financial Services, LLC.

Mr. Pfenniger has served as a director of OPKO since January 2008. Mr. Pfenniger served as CEO and President for Continucare Corporation, a provider of primary care physician and practice management services, and as Chairman of the Board of Directors of Continucare Corporation until 2011. Mr. Pfenniger has also served as the CEO and Vice Chairman of Whitman Education Group, Inc.

Prior to joining Whitman, he served as the Chief Operating Officer of IVAX and as the Senior Vice President-Legal Affairs and General Counsel of IVAX. Mr. Pfenniger currently serves as a director of GP Strategies Corporation, a corporate education and training company, TransEnterix Inc., a medical device company pioneering the use of robotics, IntegraMed America, and BioCardia, Inc., a clinical-stage regenerative medicine company. He also serves as the Vice Chairman of the Board of Trustees and as a member of the Executive Committee of the Phillip and Patricia Frost Museum of Science.

Dr. Krasno was appointed to the OPKO Board in 2017. Previously, Dr. Krasno served as executive director of the William R. Kenan, Jr. Charitable Trust and as President of the four affiliated William R. Kenan, Jr. Funds.

Prior to joining the Trust, Dr. Krasno was the President of the Monterey Institute of International Studies in Monterey, California. Dr. Krasno also served as a director of the University of North Carolina Health Care System and as chairman of the board of directors until 2012. He has also served as President and Chief Executive Officer of the Institute of International Education in New York, and as Deputy Assistant Secretary of Education in Washington, D.C.

Dr. Krasno currently serves as a director of Ladenburg Thalmann and BioCardia, Inc. and previously served as a director of Castle Brands, Inc. Dr. Krasno holds a Bachelor of Science from the University of Illinois and a Ph.D. from Stanford University.

Mr. Paganelli has served as a director of OPKO since December 2003. Previously, Mr. Paganelli served as OPKO's Interim CEO and secretary, and Chairman of OPKO's Board of Directors until 2007. Mr. Paganelli also served as President and CEO of Transamerica Life Insurance Company of New York.

Since 1987, Mr. Paganelli has been a partner in RFG Associates, a financial planning organization. Mr. Paganelli is also the Managing Partner of Pharos Systems Partners, LLC, an investment company, and served as Chairman of the Board of Pharos Systems International, a software company, from 2001 until March 2021. He was Vice President and Executive Vice President of PEG Capital Management, an investment advisory organization. Mr. Paganelli was also an officer and director-stockholder of Mike Barnard Chevrolet, Inc., an automobile dealership. Mr. Paganelli also serves as a director of Western New York Energy, LLC. Mr. Paganelli previously served on the Board of Trustees of Paul Smith's College and the Board of Managers of Bridge Financial Services, LLC.