Exhibit 21
SUBSIDIARIES OF OPKO HEALTH, INC.
 
NAME
  
JURISDICTION OF INCORPORATION
OPKO Instrumentation, LLC
  
Delaware
OPKO Pharmaceuticals, LLC
  
Delaware
OPKO Diagnostics, LLC
  
Delaware
OPKO Chile, S.A.
  
Chile
Arama Natural Products Distribuidora, Ltda
 
Chile
Pharmacos Exakta S.A. de C.V.
  
Mexico
FineTech Pharmaceutical Ltd
  
Israel
Farmadiet Group Holdings, S.C.
  
Spain
OPKO Biologics, Ltd
 
Israel
OPKO Ireland Global Holdings, Ltd
 
Ireland
OPKO Ireland, Ltd
 
Ireland
OPKO Canada Corp, ULC
 
Canada
OPKO Renal, LLC
 
Canada
Curna, Inc.
 
Delaware
BioReference Laboratories, Inc.
 
New Jersey
GeneDX, Inc.
 
New Jersey
Genome Diagnostics, Ltd
 
Canada
EirGen Pharma Limited
 
Ireland
Transition Therapeutics, Inc.
 
Canada