Form: 10-K

Annual report pursuant to Section 13 and 15(d)

March 16, 2011

Exhibit 21
SUBSIDIARIES OF OPKO HEALTH, INC.
     
NAME   JURISDICTION OF INCORPORATION
 
   
OPKO Instrumentation, LLC
  Delaware
 
   
OPKO Pharmaceuticals, LLC
  Delaware
 
   
Froptix LLC
  Florida
 
   
Ophthalmics Technology, Inc.
  Ontario, Canada
 
   
Vidus Ocular, Inc.
  Delaware
 
   
Pharma Genexx, S.A.
  Chile
 
   
Pharmacos Exakta S.A. de C.V.
  Mexico