Form: 4

Statement of changes in beneficial ownership of securities

August 15, 2007


JOINT FILER INFORMATION


 
NAME:
Frost Gamma Investments Trust
   
ADDRESS:
4400 Biscayne Blvd
 
Miami, FL 33137
   
Designated Filer:
Phillip Frost, M.D.
   
Issuer and Ticker Symbol:
Opko Health, Inc. (OPK)
   
Date of Event Requiring
 
Statement:
August 13, 2007


 


FROST GAMMA INVESTMENTS TRUST

by:
/s/ Phillip Frost, M.D.            
Phillip Frost, M.D., Trustee