Published on March 7, 2008
JOINT
FILER INFORMATION
| NAME: | Frost Gamma Investments Trust | |
| ADDRESS: | 4400 Biscayne Blvd | |
| Miami, FL 33137 | ||
| Designated Filer: | Phillip Frost, M.D. | |
| Issuer and Ticker Symbol: | Opko Health, Inc. (OPK) | |
| Date of Event Requiring Statement: | March 6, 2008 |
FROST
GAMMA INVESTMENTS TRUST
| by: | /s/ Phillip Frost MD, as trustee | |
| Phillip Frost, M.D., Trustee |