Name:	Frost Gamma Investments Trust
Address:	4400 Biscayne Blvd
	Miami, FL 33137
Designated Filer:	Phillip Frost, M.D.
Issuer Name and Ticker Symbol:	OPKO Health, Inc. (OPK)
Date of Earliest Transaction:	October 22, 2008
Relationship to Issuer:	10% Owner

	by:	/s/ Phillip Frost MD, as trustee
		Phillip Frost, M.D., Trustee