JOINT FILER INFORMATION




NAME: 				Frost Gamma Investments Trust

ADDRESS:			4400 Biscayne Blvd
				Miami, FL 33137

Designated Filer:		Phillip Frost, M.D.

Issuer and Ticker Symbol: 	Opko Health, Inc. (OPK)

Date of Event Requiring
Statement:			December 31, 2007







FROST GAMMA INVESTMENTS TRUST

	by:     /s/ Phillip Frost M.D., as trustee
		__________________________________

		Phillip Frost, M.D., Trustee