Form: S-4

Registration of securities issued in business combination transactions

July 2, 2015

Exhibit 21.1

SUBSIDIARIES OF OPKO HEALTH, INC.

 

NAME

  

JURISDICTION OF INCORPORATION

OPKO Instrumentation, LLC

   Delaware

OPKO Pharmaceuticals, LLC

   Delaware

OPKO Diagnostics, LLC

   Delaware

OPKO Chile, S.A.

   Chile

Pharmacos Exakta S.A. de C.V.

   Mexico

FineTech Pharmaceutical Ltd.

   Israel

Farmadiet Group Holdings, Ltd

   Spain

OPKO Lab, LLC

   Florida

SciVac (Israel) Ltd.

   Israel

OPKO Biologics, Ltd

   Israel

OPKO Ireland Global Holdings, Ltd

   Ireland

OPKO Ireland, Ltd

   Ireland

OPKO Canada, Inc.

   Canada

OPKO Renal, LLC

   Canada

Curna, Inc.

   Delaware

Inspiro Medical, Ltd

   Israel

OPKO do Brasil Comercio de Produtos Farmaceuticos, Ltda

   Brazil

OPKO Uruguay, Ltd

   Uruguay

EirGen Pharma Limited

   Ireland