Form: 10-K

Annual report pursuant to Section 13 and 15(d)

March 17, 2010

Exhibit 21
SUBSIDIARIES OF OPKO HEALTH, INC.
     
NAME   JURISDICTION OF INCORPORATION
     
OPKO Instrumentation, LLC
  Delaware
OPKO Ophthalmics, LLC
  Delaware
Froptix LLC
  Florida
Ophthalmics Technology, Inc.
  Ontario, Canada
Vidus Ocular, Inc.
  Delaware
Pharma Genexx, S.A.
  Chile